Weight loss has always been a hot topic. It is no surprise that there are many different products available on the market. This is to help people achieve their weight loss goals.
Yet, with so many options, deciding which is best for you can be overwhelming. Two popular weight loss medications currently on the market are Contrave and Wegovy. Their unique differences may make one a better choice for specific individuals.
This article will break down these two medications and compare them. This is to help you determine which one may be the right fit for you.
Read on to learn more about the differences between Contrave vs Wegovy.
What is Contrave?
Contrave is a combination medication that contains two active ingredients: bupropion and naltrexone. Bupropion is an antidepressant that has been shown to help with weight loss.
Contrave targets the brain's areas that control appetite and cravings. Making it easier for individuals to stick to a healthy diet and lose weight. It is available in tablet form and is taken twice a day.
What is Wegovy?
Wegovy is a newer weight loss medication approved by the FDA in 2021. Its active ingredient is semaglutide, a synthetic form of a hormone called GLP-1. This is produced in the body and helps regulate appetite and metabolism.
Wegovy mimics this hormone. Making individuals feel full faster and reducing their food intake.
Unlike Contrave, Wegovy is only available as an injection. It is more effective than other weight loss medications currently on the market. It is with clinical trials showing an average weight loss of 15-17% in participants.
Differences Between Contrave and Wegovy
Contrave and Wegovy have been proven effective in aiding weight loss. They differ in their active ingredients and how they work in the body. Here are some key differences between the two medications:
Active Ingredients
The active ingredients in these weight loss medications play crucial roles. In Contrave, bupropion works as an antidepressant. It helps in reducing appetite and cravings.
On the other hand, naltrexone is used for treating alcohol and opioid addiction. It also proves effective in curbing food cravings. This is by blocking opioid receptors in the brain.
Dosage Form
The dosage form can affect a patient's adherence to treatment. Contrave, in tablet form, is taken twice a day. This can be incorporated into a daily routine, such as taking it with breakfast and dinner.
It also requires remembering to take the medication twice a day. This could be a challenge for some individuals.
Wegovy, on the other hand, is administered through a once-weekly injection. For some, this may seem less convenient than an oral tablet.
The once-weekly dosage may be easier to remember. This may improve adherence to the medication in some individuals.
Cost
Regarding the cost of Contrave and Wegovy, it's important to note that the prices can vary widely depending on several factors, including the pharmacy where the prescription is filled, whether or not you have health insurance, and if your insurance covers weight loss medications. The monthly cost for Contrave can range from $100 to $400 without insurance coverage.
On the other hand, Wegovy tends to be more costly, with prices averaging around $1000 per month without insurance. Discussing these costs with your healthcare provider or pharmacist is crucial, as they can often suggest strategies or resources to help manage the financial burden of these medications. Also, both manufacturers of Contrave and Wegovy offer patient assistance programs that can provide the medication at a reduced cost or even free for those who qualify.
Side Effects
Both medications have potential medication side effects, but those of Contrave may include dry mouth, constipation, and nausea, while Wegovy's side effects may include headaches and gastrointestinal issues.
Detailed Side Effects
Like most medications, Contrave can cause some side effects. As previously mentioned, the most common ones include dry mouth, constipation, and nausea. It's essential to consult with your healthcare provider if you experience any of these symptoms.
Wegovy, much like Contrave, comes with its own set of potential side effects. Commonly reported side effects include nausea, diarrhea, constipation, and vomiting. Other side effects may include abdominal pain, decreased appetite, indigestion, fatigue, and dizziness.
Efficacy
Clinical trials suggest that Wegovy may be more effective than Contrave in terms of the percentage of weight loss achieved. On average, participants using Wegovy experienced a weight loss of 15-17%, while those using Contrave typically see a 5-10% weight reduction.
Use Case
Contrave is often recommended for individuals who find it hard to control their food cravings, as it works to suppress appetite and reduce cravings. On the other hand, Wegovy is a good fit for individuals who tend to eat large portions, as it helps reduce food intake by making individuals feel full faster.
Approval
Contrave has been available and approved by the FDA for weight loss for a longer time (2014) compared to Wegovy, which was only approved in 2021.
Contraindications
Contrave is contraindicated in individuals with uncontrolled high blood pressure and those with a history of seizures, while Wegovy is contraindicated in individuals with a history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2.
Which One is Right for You?
Choosing between Contrave and Wegovy ultimately depends on your personal preferences and needs. If you have a history of addiction, Contrave may not be the best choice for you, as it contains an opioid antagonist. However, if you prefer a medication that can be taken orally and more frequently throughout the week, Contrave may be a better fit.
On the other hand, if you struggle with portion control and tend to overeat, Wegovy's once-weekly injection may be a better option for you. It may also be the preferred choice for those who have trouble remembering to take medication daily.
It is important to note that both medications should be used with a healthy diet and regular exercise for optimal results. Before starting any weight loss medication, consulting with a Weight loss clinic or healthcare provider is recommended to determine the best course of action for your individual needs.
Understanding the Differences Between Contrave vs Wegovy
While Contrave vs Wegovy are both effective weight-loss medications, they have distinct differences that may make one more suitable for specific individuals. It is essential to consider these differences carefully and consult a healthcare professional before deciding which one to try.
Remember, no weight loss medication is a magic solution; lifestyle changes are necessary for long-term success. So, choose the medication that aligns with your needs and goals, and always prioritize your overall health and well-being above weight loss.
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